Cuba exported 1,934,899 packs of cigarettes in 1844. In 1848, there were 180 cigarette factories, and each of them needed to make itself distinctive.
Cuba exported 8,855,501 packs of cigarettes in 1859, each of which contained an average of 50 cigarettes. At that time, Cuba's population was less than 1.3 million.
In 1861, there were 38 cigarette factories in Havana, employing 1350 workers. Another 950 worked in the garrisons, jail and prison. That is, there were a total of 2300 people in the profession, producing 307,500 packs a day.
Because of this, José Rivero Muñiz wrote in his book Tabaco su historia en Cuba (Tobacco: its History in Cuba).

It was the tobacco industries that, for more than half a century, gave life to lithography, since no other industries ventured to use this means of advertising - either because it was expensive or perhaps because they felt that an ad in the daily press would be seen by more people. But, for whatever the reason, it is undeniable that, as I have said, if it hadn't been for the cigar and cigarette makers, the lithographic industry wouldn't have attained such broad development and prosperity.


From the Series A Visit to the La Honradez Factory - "Mechanical lithographic press"
La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
Note that the press is operated by a Chinese

The collection of lithographs entitled "A Visit to the La Honradez Factory" is very interesting from the standpoint of knowing how the marquillas were printed. US writer Samuel Hazard (1834-76) described the lithographic process used at La Honradez in greater detail in his book Cuba a pluma y lápiz (Cuba with Pen and Pencil), whose preface he completed in 1870.

In the department of lithography, drawing and engraving, I found something that I had never before seen in any other establishment and that I was assured is completely new: the process of drawing on stone by chemical and mechanical means. The apparatus is known as the "magnetic-electric machine", invented by M. E. Gaiffe, a Frenchman, who deserved to be awarded a prize in the Universal Exposition and in others. This machine, whose principle agent is electricity, is the first that has been put to practical use in this kind of industry since the days when Franklin discovered electricity. It is based on the principle of the interruption of the current by an isolating ink of which the drawing on the matrix is composed. By means of a circular motion on the part of both the surface that is to be engraved and the engraver and with the help of an electric magneto with a diamond point, a complete and perfect drawing is obtained without the need for any human work.
The special advantage of the machine is that, from now on, the artists will be able to engrave his work without having to resort to the help of an engraver or lithographer - who frequently, on copying the original, can't reproduce the particular style of the artist. With this invention, however, once the artist has made the drawing, the machine, with its electric fluid, acts in place of his hand, even when he does the work.
The number of models of cigarette packs is extraordinary - from 2000 to 3000, many of them with beautiful drawings - but the most interesting department for me was the one in which the cigarettes are made; this work is done by Chinese. Each operator has a small board on which he fills, folds, counts and makes packs of cigarettes. It is marvelous to see the ease and speed that is acquired after long practise.

Chromolithography is one of the prettiest pursuits imaginable. La Honradez was the first cigarette package labeling to use "collectible" lithographs as an enducement to buy cigarettes. In the 1850's La Honradez contracted designers and local printers to produce their labels. But an unknown someone came up with the idea of making collectible packages by issuing them in series with colored pictures.
The legions of people who collect cards, packaging and advertising owe a great debt to La Honradez, the factory who "started it all."

The most valuable collections in the José Martí National Library include three large notebooks entitled Album de cromos (Album of Prints), the first of which has 365 pages and 1460 marquillas; the second, 363 pages and 1452 lithographs; and the third, 255 pages and 1020 lithographs, a total of 3932 marquillas.

Some of the series of lithographed cigarette wrappings represented in the José Martí National Library:

1866 Almanac
African Birds
Album of Decorations and Badges of Honor
Allegories
Animal Album
Bathing in the Sea
The best from Havana - La Charanga de Villergas Division of the Llaguno and Co. Cigarette Factory, Havana
Bull Fights in Spain
Burlesque Museums
Catalonian Volunteers
The Chinese Collection
Coats of Arms of the Provinces of Spain
Comical Museum
Contemporary Gallery
Countersign - Celestino Azay's La Florida Cigarette Factory, Havana
The Crisis of 1861 - La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
Critical Museum
Cuban Birds
Cuban Children's Allegorical Drawings about Cigarettes and Cigars - La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
The Cuban Countryside - La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
Cuban Customs
Cuban Fruits - La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
Cuba's Spanish Volunteers - La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
Deck of Love - La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
The Delights of Tobacco
The Discovery of Tobacco - La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
Don Quixote
Down to Earth
English Personages
Equestrian Circus - La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
European Ballerinas - La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
European Birds
European Butterflies - La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
European Fruits
Fantasy
The Fine Arts in Caricature
The Flowers Given Life
The Fun Museum
Gallery of Famous Women
Gallery of Mithology
Gallery of Sovereignes
General view of the City of Naples
General view of the Town of Casa Blanca - Juan Rivas's Figaro Factory, Havana
The History of Tobacco - La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
Holy Story - La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
Italian Customs
Life and Death of a Mulatto Girl - La Charanga de Villergas Division of the Llaguno and Co. Cigarette Factory, Havana
Life of a Mulatto Girl - La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
The Life of Don Quixote de la Mancha
Literary Gallery - La Charanga de Villergas Division of the Llaguno and Co. Cigarette Factory, Havana
Maps of various countries
Message from the 20th Century
Military Gallery
Musical Publications
My fame flies around the world - Juan Rivas's Figaro Factory, Havana
National Flags
Ornithological Alphabet - Eduardo Guilló's Royal Cigarette Factory, Havana
Papal Court
The Paris Exposition of 1867
Postage Stamps
Prophetic Almanac for the Year 1866 - La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
Religious Habits - La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
Rural Scenes and Cities in Sweden - La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
Samaniego's Fables - La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
Samples of Sugar from my Mill - Eduardo Guilló's Royal Cigarette Factory, Havana
Scenes from Life
Scenes of Havana - La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
Scenes of our Homeland
Scenes of the World
The Seasons
Series on Mythology - Juan Rivas's Gigaro Cigarette Factory, Havana
The Seven Deadly Sins
Spanish Gallery - La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
The Spanish Navy
Spanish Personages
The Stars Given Life
Stop!
The Story of Gil Blas
Story of a Mulatto Girl - Eduardo Guilló's Royal Cigarette Factory, Havana
Sugar Mills - La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
Swiss Customs
Tapestry Designs - La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
Telegraph of Love
Telegraph of Women
Theatrical Gallery
Theatrical Museum
Uniforms of the Spanish Army - La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
Views of Havana - La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
A Visit to the La Honradez Factory - La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana
War Damage
What Happens on Earth
Zoological Alphabet - Eduardo Guilló's Royal Cigarette Factory, Havana

plus many individual scenes.


"Santiago de Cuba"
La Honradez Gran Fabrica de Cigarros de Luis Susini e Hijo, Havana

Sources:
Antoniq Núnes Jiméñez, Cuba en las Marquillas Cigarreras del Siglo XIX, Catey Ediciones turisticas de Cuba, 1985
Tony Hyman, Brandstand, CPCA, 1997